5-Iodo-UDP
(5I-UDP)
5-Iodo-uridine-5'-diphosphate, Sodium salt
Catálogo Nº | Apresentação | Preço (R$) | Comprar |
---|---|---|---|
NU-867S | 50 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
NU-867L | 5 x 50 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C9H13N2O12P2I (free acid)
Peso molecular: 530.06 g/mol (free acid)
CAS#: 34198-43-1
Pureza: ≥ 95 % (HPLC)
Forma: solution in water
Concentração: 10 mM - 11 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λmax 287 nm, ε 7.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Specific Ligands:
Selective agonistic ligand for P2Y6 receptor[1,2,3]
Referências selecionadas:
[1] Besada et al. (2006) Structure-activity relationships of uridine-5'-diphosphate analogues at the human P2Y6 receptor. J. Med. Chem. 49 (18):5532.
[2] Mamedova et al. (2008) Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation. Pharmacol. Res. 58 (3-4):232.
[3] Jacobson et al. (2009) Development of selective agonists and antagonists of P2Y receptors. Purinergic Signalling 5:75.