5-Bromo-UMP
(5Br-UMP)
5-Bromo-uridine-5'-monophosphate, Sodium salt
Catálogo Nº | Apresentação | Preço (R$) | Comprar |
---|---|---|---|
NU-135S | 100 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
NU-135L | 5 x 100 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C9H12BrN2O9P (free acid)
Peso molecular: 403.08 g/mol (free acid)
CAS#: 2149-79-3
Pureza: ≥ 95 % (HPLC)
Forma: solution in water
Concentração: 10 mM - 11 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λmax 278 nm, ε 9.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Referências selecionadas:
Labesse et al. (2011) Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation. Nucleic Acids Res. 39 (8):3458.
Gilles et al. (2007) Regulatory Mechanisms Differ in UMP Kinases from Gram-negative and Gram-positive Bacteria. J. Biol. Chem. 282 (10):7242.
Kwon et al. (1999) Bipartite modular structure of intrinsic, RNA hairpin-independent termination signal for phage RNA polymerases. J. Biol. Chem. 274 (41):29149.
Tourneux et al. (1998 ) Substitution of an alanine residue for glycine 146 in TMP kinase from Escherichia coli is responsible for bacterial hypersensitivity to bromodeoxyuridine. J. Bacteriol. 180 (16):4291.