EDA-GDP-BDP-FL
also known as BODIPY® FL-GDP
2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-diphosphate, labeled with BODIPY® FL, Triethylammonium salt
Catálogo Nº | Apresentação | Preço (R$) | Comprar / Observação |
---|---|---|---|
NU-840-BDP | 50 μl (5 mM) | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C27H34BF2N9O13P2 (free acid)
Peso molecular: 803.37 g/mol (free acid)
Pureza: ≥ 95 % (HPLC)
Forma: solution in water
Concentração: 5.0 mM - 5.5 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λexc 503 nm, λem 512 nm, ε 80.0 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Referências selecionadas:
Hong et al. (2015) A Pan-GTPase Inhibitor as a Molecular Probe. PLoS One. 10 (8):e0134317.
Sekine et al. (2015) Mutations in a translation initiation factor identify target of a memory-enhancing compound. Science. 348 (6238):1027.
Evelyn et al. (2014) Rational design of small molecule inhibitors targeting the Ras GEF, SOS1. Chem. Biol. 21 (12):1618.
Shimizu et al. (2014) Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding. J. Biol. Chem. 292 (32):13441.
Wilden et al. (2006) Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome. Proc. Natl. Acad. Sci. USA 103 (37):13670.