Ac4GlcNAz
N-azidoacetylglucosamine-tetraacylated (Ac4GlcNAz)
Catálogo Nº | Apresentação | Preço (R$) | Comprar |
---|---|---|---|
CLK-1085-5 | 5 mg | Sob demanda | Adicionar ao Carrinho |
CLK-1085-25 | 25 mg | Sob demanda | Adicionar ao Carrinho |
CLK-1085-100 | 100 mg | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped at ambient temperature
Condições de armazenamento: store at -20 °C
Validade: 12 months after date of delivery
Fórmula molecular: C16H22N4O10
Peso molecular: 430.37 g/mol
CAS#: 98924-81-3
Pureza: mass identification (ESI-MS)
Forma: amorphous solid
Solubilidade: DMSO, DMF, MeOH
Formulários:
Glycoconjugate synthesis monitoring by metabolic labeling
Descrição:
The tetraacetylated N-Azidoacetyl-glucosamine (Ac4GlcNAz) provides a non-radioactive alternative for glycoconjugate visualization. It is cell-permeable, intracellularly processed and incorporated instead of its natural monosaccharide counterpart N-Acetylglucosamine(GlcNAc).
The resulting Azide-functionalized glycoconjugates can subsequently be detected via Cu(I)-catalyzed or Cu(I)-free Click Chemistry that offers the choice to introduce a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or to introduce fluorescent group (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent microscopic imaging.
Recommended concentration for metabolic labeling: 25-75 μM. This concentration range may serve as a starting point for an individual assay set-up.